Polypeptide Architecture.

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Pancreatic polypeptide.

Pancreatic polypeptide (PP) was discovered fortuitously during the purification of insulin from birds (Kimmel et al., 1968) and later from mammals (Chance et al., 1976). PP has since been extracted and purified from several mammalian species. It contains 36 amino-acid residues and is quite distinct from other known hormonal peptides (Lin and Chance, 1974). The amino-acid sequence of the peptide...

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Pancreatic Polypeptide

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Glucose-Dependent Insulinotropic Polypeptide

OBJECTIVE To evaluate the glucose dependency of glucose-dependent insulinotropic polypeptide (GIP) effects on insulin and glucagon release in 10 healthy male subjects ([means ± SEM] aged 23 ± 1 years, BMI 23 ± 1 kg/m(2), and HbA(1c) 5.5 ± 0.1%). RESEARCH DESIGN AND METHODS Saline or physiological doses of GIP were administered intravenously (randomized and double blinded) during 90 min of ins...

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ژورنال

عنوان ژورنال: Kobunshi

سال: 1994

ISSN: 0454-1138,2185-9825

DOI: 10.1295/kobunshi.43.616